MORF4L2 anticorps (N-Term)
Aperçu rapide pour MORF4L2 anticorps (N-Term) (ABIN374201)
Antigène
Voir toutes MORF4L2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody detects MORF4L2 at N-term.
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Réactivité croisée (Details)
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Species reactivity (expected):Canine.
Species reactivity (tested):Human. -
Purification
- Affinity chromatography
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Immunogène
- Peptide with sequence SSRKQGSQPRGQQS-C, from the N Terminus of the protein sequence Genename: MORF4L2
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Indications d'application
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Peptide ELISA: 1/32000. Western blot: 1 - 3 μg/mL. Approx 35 kDa band observed in Human Brain and A431 lysates(calculated MW of 32.5 kDa according to NP_036418.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))
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Autre désignation
- MORF4L2
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Sujet
- Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes mainly by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also be involved in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones. May also interact with one or more as yet undefined members of the TLE (transducin like enhancer of split) family of transcriptional repressors.Synonyms: KIAA0026, MORF-related gene X protein, MORF4L2, MRGX, MSL3-2 protein, Mortality factor 4-like protein 2, Transcription factor-like protein MRGX
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ID gène
- 9643
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NCBI Accession
- NP_036418
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UniProt
- Q15014
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Pathways
- Regulation of Muscle Cell Differentiation
Antigène
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